Formylation of indoles with formic acid.

Treatment of Warts with Topical Formic Acid

Clean and Green Approach for N-formylation of Amines using Formic acid under neat reaction condition

In recent years much effort has been carried out on formylations of amines. N-formyl compounds have been widely used in organic synthesis as protecting group of amines [1]. They are also used for synthesis of pharmaceutically important heterocylces [2-5]. Formamides are the Lewis bases, which are known to catalyze reactions such as allylations [6] and hydrosilylations [7] of carbonyl compounds....

The ammonium-promoted formylation of indoles by DMSO and H2O.

DMSO and H2O is an efficient combination in the NH4OAc-promoted formylation of indole, where DMSO serves as a C1 carbon source. The mechanism study reveals that the procedure involves a usual and unusual Pummerer reaction.

Reaction of atomic hydrogen with formic acid.

We study the reaction of atomic hydrogen with formic acid and characterize the radical products using IR spectroscopy in a Kr matrix and quantum chemical calculations. The reaction first leads to the formation of an intermediate radical trans-H2COOH, which converts to the more stable radical trans-cis-HC(OH)2via hydrogen atom tunneling on a timescale of hours at 4.3 K. These open-shell species ...

treatment of warts with topical formic acid

0